A Non-smoking Woman with Anti-phospholipid Antibodies Proved to Have Thromboangiitis Obliterans

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Thromboangiitis obliterans with cryoglobulinemia.

Thromboangiitis obliterans (TAO), or Buerger's disease, is a vascular occlusive disease associated with cigarette smoking. It typically affects medium sized vessels of extremities. Basic pathology of TAO is described to be endothelial activation with highly inflammatory intraluminal thrombosis preserving internal elastic membrane. Cryoglobulins are immunoglobulins that precipitate in the cold a...

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Thromboangiitis obliterans.

Case presentation: A 39-year-old male smoker with a 2-year history of calf discomfort on ambulation culminating in left femoral-to-peroneal artery bypass presented with right leg discomfort and recurrent painful subcutaneous nodules on his feet and calves. Biopsy of a nodule from his right foot was interpreted as vasculitis with thrombosis and fibrinoid necrosis in subcutaneous vessels, and the...

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Thromboangiitis obliterans.

Thromboangiitis obliterans (TAO) has been a recognized clinical entity for more than half a century (Buerger, 1908). Distal arterial occlusive disease and/or recurrent superficial thrombophlebitis occurring in an adult male smoker, in the absence of known cause, constitutes a distinctive and unmistakable syndrome (Brown, Allen, and Mahorner, 1928). However, the existence of this disorder has be...

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Cerebral thromboangiitis obliterans.

A stroke due to vascular occlusion in a young person can raise many diagnostic and prognostic problems. In the following case report hemiplegia of sudden onset occurred in a young man followed by partial recovery without a definite diagnosis being made, despite full investigation. Further progression of the disease leading to death two years later enabled a complete pathological investigation t...

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Thromboangiitis obliterans (Buerger's disease)

Thromboangiitis Obliterans is a non-atherosclerotic inflammatory disease of unknown etiology, which has a strong association with tobacco. We present current concepts on the pathophysiology and diagnosis, as well as a review in treatments.

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ژورنال

عنوان ژورنال: Internal Medicine

سال: 2020

ISSN: 0918-2918,1349-7235

DOI: 10.2169/internalmedicine.3372-19